Professor Dubrow has been heavily involved in the educational mission of Yale School of Public Health, as well as in research. Moved by what he sees as the greatest public health challenge in this century, Dubrow has committed himself to a new direction of education, training, and research on climate change and health. He serves as Faculty Director for The Yale Center on Climate Change and Health (CCCH), which aims to 1) create a cohort of leaders dedicated to addressing climate change and health; 2) establish an educational program on climate change and health for students across the University; 3) catalyze research on climate change and health utilizing Yale’s multidisciplinary expertise to generate innovative interventions and policy prescriptions; and 4) utilize public health science to support legislative, litigative, regulatory, executive, community, and other efforts to mitigate or adapt to climate change and to achieve climate justice. Dubrow serves on the Advisory Board of Cool Effect, a program that identifies some of the best carbon emission reduction projects in the world and makes it simple for supporters to donate.

Dubrow has taught both Principles of Epidemiology I and Principles of Epidemiology II and was chosen by the Classes of 2002, 2007, and 2012 to be Teacher of the Year. He co-Chaired the Yale School of Public Health Accreditation Advisory Committee, which oversaw the School's self-study process leading up to its successful 7-year re-accreditation by the Council on Education for Public Health in 2014.

Historically, Dubrow's research has focused on cancer, HIV, and their intersection. Most recently, his research has focused on two distinct areas: glioma (the main form of brain cancer) and HIV-related malignancies. He is currently developing a research and public health practice program in the area of climate change and health.